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Given that the liver is the primary site for IGF-1 synthesis and secretion, it is logical to expect that liver-related abnormalities, such as cirrhosis, could exert an influence on IGF-1 concentration [Citation32]

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Understanding Constipation on GLP-1 Medications Constipation on GLP-1 is a common issue because these medications slow digestion

Alzheimers Dement 2017;13:1-7

However, because the plasma is further processed and diluted when manufactured into therapies, and because GLP-1s are not known to be harmful to the general population of plasma recipients, it is not considered a safety risk by major collection centers